الأبحاث العلمية

  1. Al Doghaither, H.A., Al-Sohaibani, R.M., Omar, U.M., Al-Harbi, H.A., (2021). Biochemical and histological studies on the effects of five weeks ingestion of Zamzam water on the liver and kidneys of Wistar rats. Saudi Pharmaceutical Journal. Accepted.
  2. Elmorsy, E., Al-Ghafari, A., Al Doghaither, H. Ghulam, J. (2021). Effects of environmental metals on mitochondrial bioenergetics of the CD-1 mice pancreatic ꞵ-cells. Toxicology in Vitro. 70, 105015.  
  3. Al Doghaither, H., Elmorsy, E., Al-Ghafari, A., Ghulam, J. (2021). Roles of oxidative stress, apoptosis, and inflammation in metals-induced dysfunction of beta pancreatic cells isolated from CD1 mice. Saudi Journal of Biological Sciences. 28 (1), 651-663.
  4. Bakhrebah, M, Nasrullah, M. Abdulaal, W.H., Hassan, M.A., Siddiqui, H., Al Doghaither, H.A., Omar, U.M. Helmi, N., Fallatah, M.M., Al-Ghafari, A.B., Khan, M.I., and Choudhry, H. (2020). High expression of PD-1 in circulating cells of patients with advanced colorectal Cancer receiving adjuvant therapy. Technology in Cancer Research and Treatment. 19, 1-7.
  5. Al-Ghafari, A.B., Al Qahtani, A.M., Alturki, S., Al Doghaither, H.A., Elmorsy, E.M., Tashkandi, H.M., Abusanad, A.M., Alkhayyat, S.S., Omar, U.O., Zeeneldin, A.M. (2020). The association of MDR1 polymorphisms to Xeliri and Xelox chemoresistance in Saudi colorectal cancer patients. Oncology Letters. 20, 155.
  6. Al-Ghafari, A.B., Balamash, K.B., and Al Doghaither, H.A. (2020). TaqI and ApaI variants in vitamin D receptor (VDR) gene increase the risk of colorectal cancer. Saudi Journal of Medicine and Medical Sciences. 8(3): 188-195.
  7. Qutub, R. Al-Ghafari, A. and Al Doghaither, H., Omar, U., Ghulam, G. (2020). Increased expressions of ATP-binding cassette transporters might be a promising diagnostic marker for colorectal cancer. Saudi Medical Journal. 41(8): 179-185. 
  8. Al-Nowaihi, S., Al Doghaither, H., and Noor, N. (2020). Visfatin concentrations and its relationship with sex hormones in obese Saudi Women. Int J Heal Sci (Qassim). 14(3): 9-13
  9. Gull, M., Muharram, E.B., Shaik, N.A., Al Mahdi, H.B., and Bondagi, N.S., Al Doghaither, H.A. (2020). Assessment of Insertion/deletion polymorphism of ACE gene as a genetic risk marker for preeclampsia in pregnant women. Journal of Pakistan Medical Associations. 70: 791-795.
  10. Balkhair, A.M., Al-Ghafari A.B., Yezerski, A., Tashkandi, H., Alturki, S., Al Doghaither, H., Abusanad, A., Alkhayyat, S., and Zeeneldin, A. (2020). Contribution of ABCG2 gene polymorphisms (A34G and C376T) with the prognosis of colorectal cancer. Indian Journal of Biochemistry and biophysics. 57:73-78
  11. Al-Ghafari, A.B., Balamash, K.B., and Al Doghaither, H.A. (2020). Serum vitamin D receptor (VDR) levels as a potential diagnostic marker for colorectal cancer. Saudi Journal of Biological Sciences. 27: 827-832.
  12. Alsahafi, M.A., Al-Ghafari, A.B., Al Doghaither, H.A., Omar, U.M., Abusanad, A.M., Khayyat, S., Elmorsy E.A., Tashkandi, H.M. (2020). Serum levels of Apolipoprotein E in colorectal cancer patients and its relationship with the diagnosis of the disease. The Annals of Clinical and Analytical Medicine. DOI:10.4328/ ACAM.20092
  13. Al-Harbi, M.F., Al-Ghafari, A.B., Al Doghaither, H.A., Alshaibi, H.F., Omar, U.M. (2020). Contribution of Apolipoprotein E isoforms to colorectal cancer carcinogenesis. Pakistan Journal of Biological Sciences. 23(3): 306-312
  14. Al Zahrani, S.M., Omar, U.M., Rahimulddin, S.A., Al-Ghafari, A.B., and Al Doghaither, H.A. (2019). Anti-proliferative and apoptotic effects of the natural alkaline water (Zamzam) in breast cancer cell line MCF-7. Journal of Cancer Research and Therapeutics. 15(5): 1098-1104.
  15. Siddiqui, H., Al-Ghafari, A. Choudhry, H., and Al Doghaither, H. (2019). Roles of long non-coding RNAs (lncRNAs) in colorectal cancer tumorigenesis. Molecular and Clinical Oncology. 11(2): 176-172.
  16. Al Qahtani, A.M., Al-Ghafari, A.B., Al Doghaither, H.A., Alzahrani, A.H., Omar, U.M., and Rahimulddin, S.A. (2019). ABCB1 variants C3435T and T129C are not associated with colorectal cancer risk. African Health Sciences. 19(3): 2476-2483.
  17. Al Doghaither, H., Alshaikh, E., Omar, U., Mansouri, R., Alsufiani, H., Tarbiah, N., Alshaikh, A., and Alshaikh, A. (2019). Insulin resistance and its correlation with chemerin and visfatin in Saudi patients with hyperthyroidism. International Journal of Health Sciences. 13(5): 18-21.
  18. Al-Ghafari, A., Balamash, K., and Al Doghaither, H. Relationship between serum levels of vitamin D and calcium with vitamin D receptor gene polymorphisms in colorectal cancer. BioMed Research International. Vol. 2019, Article ID 8571541, 8 pages, 2019.
  19. Alshaikh, E., Omar, U., Alsufiani, H., Mansouri, R., Tarbiah, N., Alshaikh, A., Rahimulddin, S., and Al Doghaither, H. (2019). The potential influence of hyperthyroidism on circulating adipokines; chemerin, visfatin and omentin. International Journal of Health Sciences. 13(2): 44-47.
  20. Siddiqui, H., Al-Ghafari, A., Choudhry, H., AlTurki, S., Alshibi, H., Al Doghaither, H., and Alsufiani H. (2019). Long Non-Coding RNAs as Prognostic Markers for Colorectal Cancer in Saudi Patients. Genetic Testing and Molecular Biomarkers. 23(8): 509-514.
  21. Abdulkhaleq, M.M., Al-Ghafari, A.B., Ann Yezerski, A., Al Doghaither, H.A., Abusanad, A.M., and Omar, U.M. (2019). Novel association between heterozygous genotype of SNP C218T in drug transporter ABCC1 gene and increased risk of colon cancer. Saudi Medical Journal. 40(3): 179-185.
  22. Al Doghaither, H., and Al-Ghafari, A. (2018). Contribution of genetic variants of ABC transporters (ABCC1 and ABCG2) genes with the pathogenesis of colorectal cancer. Biosciences Biotechnology Research Asia. 15(3): 555-559.
  23. Iyer, A.P., New, S.L., Khoja, S., Al-Ghamdi M., and Al Doghaither, H.A. (2017). Relationship between Vitamin D receptor gene polymorphisms and type 1 diabetes mellitus in Saudi patients. International Journal of Pharmacology. 13(8): 1092- 1097.
  24. Al-Garni A.A., Rahimulddin, S.A., Omar U.M., Al Doghaither, H.A., and Al-Harbi, H.A. (2017). Evaluation of the antioxidant activities of aqueous extracts of fresh Madeni rose petals. International Journal of Science and Nature. 8(3): 461-468.
  25. Alsulami, S.O., Al Doghaither, H.A., and Iyer, A.P. (2017). Detection of methicillin resistant Staphylococcus aureus Isolated from nasal carriage of health care workers by polymerase chain reaction. Journal of Experimental Biology and Agricultural Science. 5(3): 288-293.
  26. Eid, N., Al Doghaither, H., Kumosani, T., and Gull, M. (2017). Diversity, physiochemical and phylogenetic analyses of bacteria isolated from various drinking water sources. Pakistan Journal of Medical Sciences. 33(3): 703-708.
  27. Omar, U.M., Al Doghaither, H.A., Rahimulddin, S.A., Al Zahrani, S.M., and Al-Ghafari, A.B. (2017). In vitro cytotoxic and anticancer effects of Zamzam water in human lung cancer (A594) cell line. Malaysian Journal of Medical Sciences. 24(3): 15-25.
  28. Al Doghaither, H.A., Alyousef, M.M., Al Selami, N.M., Al-Ghafari, A.B., and Omar, U.M. (2017). Addition of evaporated milk alters antioxidant properties of the most commonly consumed coffee in Saudi Arabia. Malaysian Applied Biology. 46(2): 97-104.
  29. Al Doghaither, H.A., and Al-Malki, E. (2017). The addition of herbal additives influences the antioxidant activity of Arabic coffee. World Applied Sciences Journal. 35(3): 393-398.
  30. Al Doghaither, H.A., Almowalad, A.M., Shorbaji, A.M., Al-Ghafari, A.B., and Omar, U.M. (2017). Assessment of the antioxidant properties of the most common coffee brews available in the local markets of the western region of Saudi Arabia. Journal of Experimental Biology and Agricultural Science. 5(1): 70-76.
  31. Al-Ghafari, A.B., Alharbi, R.H., Al-Jehani, M.M., Bujeir, S.A., Al Doghaither, H.A., and Omar, U.M. (2017). The Effect of adding different concentrations of cows’ milk on the antioxidant properties of coffee. Biosciences Biotechnology Research Asia. 14(1):177-184.
  32. Al-Ghamdi, M.A., Choudhry, H., Al Doghaither, H.A., Huwait, E., Kumosani, T.A., and Moselhy, S.M. (2017). Potential administration of lipoic acid and coenzyme Q against adipogensis: Target for weight reduction. African Journal of Traditional, Complementary and Alternative Medicine. 14(1): 272-277.
  33. Al Doghaither, H.A., Omar, U.M., Rahimulddin, S.A., and Al-Ghafari, A.B. (2016). The cytotoxic effects of aqueous extracts of Urtica urens on most common cancer types in Saudi Arabia. Journal of Biological Sciences. 16(6): 242-246.
  34. Rahimulddin, S.A., Al-Ghafari, A.B., Al Doghaither, H.A., Omar, U.M., and Al Zahrani, S.M. (2016). The influence of pH and sterilization conditions on the inhibitory effects of Zamzam water on the cell viability of cancer cells. J Biol Sci. 16(6): 229-235.
  35. Al Doghaither, H.A., Al-Ghafari, A.B., Rahimulddin, S.A., Al Zahrani, S.M., Omar, A.M., and Omar, U.M. (2016). Evaluation of the potential anticancer activity of Zamzam water in human colon cancer cell line. Cancer and Oncology Research 4(3): 33-41.
  36. Al-Ghafari, A.B., Shorbaji, A.M., Sarori, L.A., Baduwailan, E.O., Basaar, A.A., Al Doghaither, H.A., Al-Marzouki, H.F., and Omar, U.M. (2016) Phenolic contents and the antioxidant activities of green tea with and without lemon. Natural Science. 7: 247-255.
  37. Omar, U.M., Shorbaji, A.M., Arrait, E.M., Al Agha, T.D., Al-Marzouki, H.F., Al Doghaither, H.A., and Al-Ghafari, A.B. (2016) Comparative study of the antioxidant activity of two popular green tea beverages available in the local market of Saudi Arabia. Natural Science. 8: 227-234.
  38. Baeshin, N., Lari, S., Al-Doghaither, H.A., and Ramadan, H.A. (2010). Effect of Rhazya stricta extract on rat adiponectin gene and insulin resistance. Journal of American Science. 6(12): 1237-1245.
  39. Baeshin, N., Lari, S., Al-Doghaither, H.A., and Elkady, A. (2009). Effects of aqueous extracts of Rhazya stricta on blood lipid profile concentrations, liver enzyme activities and kidney functions in rats. Journal of Applied Sciences Research. 5(9): 1103-1109.
  40. Al-Harithy, R.N., Al-Doghaither, H.A., and Abualnaja, K. (2006). Correlation of leptin and sex hormones with endocrine changes in healthy Saudi women of different body weights. Annals of Saudi Medicine. 26(2): 110-115.

آخر تحديث
10/16/2020 1:39:05 PM